Suzuki-Miyaura cross-coupling coupling reactions with low catalyst loading: A green and sustainable protocol in pure water

Handle URI:
http://hdl.handle.net/10754/561649
Title:
Suzuki-Miyaura cross-coupling coupling reactions with low catalyst loading: A green and sustainable protocol in pure water
Authors:
Fihri, Aziz; Luart, Denis; Len, Christophe; Solhy, Abderrahim; Chevrin, Carole; Polshettiwar, Vivek ( 0000-0003-1375-9668 )
Abstract:
The Suzuki-Miyaura coupling reaction represents one of the most important synthetic transformations developed in the 20th century. However, the use of toxic organic solvents remains a scientific challenge and an aspect of economical and ecological relevance, and benign water as a reaction medium was found to be highly effective to overcome some of these issues. In the present manuscript, we described Suzuki-Miyaura coupling reactions in neat water, without using any phase transfer reagent. Notably, this protocol also works with ultra-low loading of catalyst with high turnover numbers and also able to couple challenging substrates like aryl chlorides. © 2011 The Royal Society of Chemistry.
KAUST Department:
KAUST Catalysis Center (KCC); Physical Sciences and Engineering (PSE) Division
Publisher:
Royal Society of Chemistry (RSC)
Journal:
Dalton Transactions
Issue Date:
2011
DOI:
10.1039/c0dt01637c
PubMed ID:
21340087
Type:
Article
ISSN:
14779226
Sponsors:
The authors acknowledge Ayoub Hassine for experimental work during his Master's training and the Region Picardie for their financial support.
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; KAUST Catalysis Center (KCC)

Full metadata record

DC FieldValue Language
dc.contributor.authorFihri, Azizen
dc.contributor.authorLuart, Denisen
dc.contributor.authorLen, Christopheen
dc.contributor.authorSolhy, Abderrahimen
dc.contributor.authorChevrin, Caroleen
dc.contributor.authorPolshettiwar, Viveken
dc.date.accessioned2015-08-03T09:01:22Zen
dc.date.available2015-08-03T09:01:22Zen
dc.date.issued2011en
dc.identifier.issn14779226en
dc.identifier.pmid21340087en
dc.identifier.doi10.1039/c0dt01637cen
dc.identifier.urihttp://hdl.handle.net/10754/561649en
dc.description.abstractThe Suzuki-Miyaura coupling reaction represents one of the most important synthetic transformations developed in the 20th century. However, the use of toxic organic solvents remains a scientific challenge and an aspect of economical and ecological relevance, and benign water as a reaction medium was found to be highly effective to overcome some of these issues. In the present manuscript, we described Suzuki-Miyaura coupling reactions in neat water, without using any phase transfer reagent. Notably, this protocol also works with ultra-low loading of catalyst with high turnover numbers and also able to couple challenging substrates like aryl chlorides. © 2011 The Royal Society of Chemistry.en
dc.description.sponsorshipThe authors acknowledge Ayoub Hassine for experimental work during his Master's training and the Region Picardie for their financial support.en
dc.publisherRoyal Society of Chemistry (RSC)en
dc.titleSuzuki-Miyaura cross-coupling coupling reactions with low catalyst loading: A green and sustainable protocol in pure wateren
dc.typeArticleen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.identifier.journalDalton Transactionsen
dc.contributor.institutionTransformat Integrees Mat Renouvelable ESCOM UTC, F-60200 Compiegne, Franceen
dc.contributor.institutionENSET, MAScIR Fdn, INANOTECH, Rabat 10100, Moroccoen
kaust.authorFihri, Azizen
kaust.authorPolshettiwar, Viveken

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