Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes

Handle URI:
http://hdl.handle.net/10754/561646
Title:
Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes
Authors:
Wang, Fei; Zhang, Wei; Zhu, Jieming; Li, Huaifeng ( 0000-0001-9661-803X ) ; Huang, Kuo-Wei ( 0000-0003-1900-2658 ) ; Hu, Jinbo
Abstract:
A chloride ion-catalyzed generation of difluorocarbene from a relatively non-toxic and inexpensive precursor, Me3SiCF2Cl (1), under mild and neutral conditions leads to an efficient preparation of gem-difluorocyclopropenes and difluorocyclopropanes through [2 + 1] cycloaddition reactions with alkynes and alkenes, respectively. © 2011 The Royal Society of Chemistry.
KAUST Department:
Biological and Environmental Sciences and Engineering (BESE) Division; KAUST Catalysis Center (KCC); Chemical Science Program; Physical Sciences and Engineering (PSE) Division; HCL
Publisher:
Royal Society of Chemistry (RSC)
Journal:
Chem. Commun.
Issue Date:
2011
DOI:
10.1039/c0cc04548a
PubMed ID:
21170456
Type:
Article
ISSN:
13597345
Sponsors:
This work was supported by CAS and NFSC (20772144, 20825209, 20832008) to J.H. and by a KAUST baseline funding to K.-W.H.
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; Chemical Science Program; KAUST Catalysis Center (KCC); Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorWang, Feien
dc.contributor.authorZhang, Weien
dc.contributor.authorZhu, Jiemingen
dc.contributor.authorLi, Huaifengen
dc.contributor.authorHuang, Kuo-Weien
dc.contributor.authorHu, Jinboen
dc.date.accessioned2015-08-03T09:01:17Zen
dc.date.available2015-08-03T09:01:17Zen
dc.date.issued2011en
dc.identifier.issn13597345en
dc.identifier.pmid21170456en
dc.identifier.doi10.1039/c0cc04548aen
dc.identifier.urihttp://hdl.handle.net/10754/561646en
dc.description.abstractA chloride ion-catalyzed generation of difluorocarbene from a relatively non-toxic and inexpensive precursor, Me3SiCF2Cl (1), under mild and neutral conditions leads to an efficient preparation of gem-difluorocyclopropenes and difluorocyclopropanes through [2 + 1] cycloaddition reactions with alkynes and alkenes, respectively. © 2011 The Royal Society of Chemistry.en
dc.description.sponsorshipThis work was supported by CAS and NFSC (20772144, 20825209, 20832008) to J.H. and by a KAUST baseline funding to K.-W.H.en
dc.publisherRoyal Society of Chemistry (RSC)en
dc.titleChloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanesen
dc.typeArticleen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.contributor.departmentChemical Science Programen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentHCLen
dc.identifier.journalChem. Commun.en
dc.contributor.institutionKey Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Ling-Ling Road, Shanghai 200032, Chinaen
kaust.authorLi, Huaifengen
kaust.authorHuang, Kuo-Weien

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