Challenges and Opportunities of Airborne Metagenomics

Handle URI:
http://hdl.handle.net/10754/553005
Title:
Challenges and Opportunities of Airborne Metagenomics
Authors:
Behzad, H.; Gojobori, Takashi ( 0000-0001-7850-1743 ) ; Mineta, K.
Abstract:
Recent metagenomic studies of environments, such as marine and soil, have significantly enhanced our understanding of the diverse microbial communities living in these habitats and their essential roles in sustaining vast ecosystems. The increase in the number of publications related to soil and marine metagenomics is in sharp contrast to those of air, yet airborne microbes are thought to have significant impacts on many aspects of our lives from their potential roles in atmospheric events such as cloud formation, precipitation, and atmospheric chemistry to their major impact on human health. In this review, we will discuss the current progress in airborne metagenomics, with a special focus on exploring the challenges and opportunities of undertaking such studies. The main challenges of conducting metagenomic studies of airborne microbes are as follows: 1) Low density of microorganisms in the air, 2) efficient retrieval of microorganisms from the air, 3) variability in airborne microbial community composition, 4) the lack of standardized protocols and methodologies, and 5) DNA sequencing and bioinformatics-related challenges. Overcoming these challenges could provide the groundwork for comprehensive analysis of airborne microbes and their potential impact on the atmosphere, global climate, and our health. Metagenomic studies offer a unique opportunity to examine viral and bacterial diversity in the air and monitor their spread locally or across the globe, including threats from pathogenic microorganisms. Airborne metagenomic studies could also lead to discoveries of novel genes and metabolic pathways relevant to meteorological and industrial applications, environmental bioremediation, and biogeochemical cycles.
KAUST Department:
Computational Bioscience Research Center (CBRC); Biological and Environmental Sciences and Engineering (BESE) Division; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Citation:
Challenges and Opportunities of Airborne Metagenomics 2015, 7 (5):1216 Genome Biology and Evolution
Publisher:
Oxford University Press (OUP)
Journal:
Genome Biology and Evolution
Issue Date:
6-May-2015
DOI:
10.1093/gbe/evv064
Type:
Article
ISSN:
1759-6653
Additional Links:
http://gbe.oxfordjournals.org/cgi/doi/10.1093/gbe/evv064
Appears in Collections:
Articles; Computational Bioscience Research Center (CBRC); Biological and Environmental Sciences and Engineering (BESE) Division; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorBehzad, H.en
dc.contributor.authorGojobori, Takashien
dc.contributor.authorMineta, K.en
dc.date.accessioned2015-05-17T20:21:48Zen
dc.date.available2015-05-17T20:21:48Zen
dc.date.issued2015-05-06en
dc.identifier.citationChallenges and Opportunities of Airborne Metagenomics 2015, 7 (5):1216 Genome Biology and Evolutionen
dc.identifier.issn1759-6653en
dc.identifier.doi10.1093/gbe/evv064en
dc.identifier.urihttp://hdl.handle.net/10754/553005en
dc.description.abstractRecent metagenomic studies of environments, such as marine and soil, have significantly enhanced our understanding of the diverse microbial communities living in these habitats and their essential roles in sustaining vast ecosystems. The increase in the number of publications related to soil and marine metagenomics is in sharp contrast to those of air, yet airborne microbes are thought to have significant impacts on many aspects of our lives from their potential roles in atmospheric events such as cloud formation, precipitation, and atmospheric chemistry to their major impact on human health. In this review, we will discuss the current progress in airborne metagenomics, with a special focus on exploring the challenges and opportunities of undertaking such studies. The main challenges of conducting metagenomic studies of airborne microbes are as follows: 1) Low density of microorganisms in the air, 2) efficient retrieval of microorganisms from the air, 3) variability in airborne microbial community composition, 4) the lack of standardized protocols and methodologies, and 5) DNA sequencing and bioinformatics-related challenges. Overcoming these challenges could provide the groundwork for comprehensive analysis of airborne microbes and their potential impact on the atmosphere, global climate, and our health. Metagenomic studies offer a unique opportunity to examine viral and bacterial diversity in the air and monitor their spread locally or across the globe, including threats from pathogenic microorganisms. Airborne metagenomic studies could also lead to discoveries of novel genes and metabolic pathways relevant to meteorological and industrial applications, environmental bioremediation, and biogeochemical cycles.en
dc.publisherOxford University Press (OUP)en
dc.relation.urlhttp://gbe.oxfordjournals.org/cgi/doi/10.1093/gbe/evv064en
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.comen
dc.subjectairborne microorganismsen
dc.subjectculture-independent studiesen
dc.subjectmicrobial diversityen
dc.subjectmetagenomicsen
dc.subject16S rRNA sequencingen
dc.subjectmetabolic potentialen
dc.titleChallenges and Opportunities of Airborne Metagenomicsen
dc.typeArticleen
dc.contributor.departmentComputational Bioscience Research Center (CBRC)en
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Divisionen
dc.identifier.journalGenome Biology and Evolutionen
dc.eprint.versionPublisher's Version/PDFen
kaust.authorGojobori, Takashien
kaust.authorMineta, Katsuhikoen
kaust.authorBehzad, Hayedehen
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