A biodetection method using magnetic particles and micro traps

Handle URI:
http://hdl.handle.net/10754/552839
Title:
A biodetection method using magnetic particles and micro traps
Authors:
Li, Fuquan ( 0000-0002-1573-597X ) ; Giouroudi, Ioanna; Kosel, Jürgen ( 0000-0002-8998-8275 )
Abstract:
The general working principle of magnetoresistive sensors for biological applications is to specifically attach bioanalytesto magnetic particles and then detect the particles that are immobilized on the sensor surface. The immobilization of the particles on the sensor surface commonly uses biomolecular interactions, e.g., antigen-antibody. Thus, the sensor surface needs to be functionalized via biological treatments in order to capture certain bioanalytes. In the presented work, a new method is proposed, which does not rely on functionalization of the sensor surface. Current carrying microstructures in combination with mechanical micro traps are used to immobilize magnetic particles. Analyte detection is based on the difference in size between bare magnetic particles and particles with analyte attached, which causes a different number of particles to be captured in the micro traps.
KAUST Department:
Physical Sciences and Engineering (PSE) Division
Citation:
A biodetection method using magnetic particles and micro traps 2012, 111 (7):07B328 Journal of Applied Physics
Journal:
Journal of Applied Physics
Issue Date:
9-Mar-2012
DOI:
10.1063/1.3678304
Type:
Article
ISSN:
00218979
Additional Links:
http://scitation.aip.org/content/aip/journal/jap/111/7/10.1063/1.3678304
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorLi, Fuquanen
dc.contributor.authorGiouroudi, Ioannaen
dc.contributor.authorKosel, Jürgenen
dc.date.accessioned2015-05-14T08:49:28Zen
dc.date.available2015-05-14T08:49:28Zen
dc.date.issued2012-03-09en
dc.identifier.citationA biodetection method using magnetic particles and micro traps 2012, 111 (7):07B328 Journal of Applied Physicsen
dc.identifier.issn00218979en
dc.identifier.doi10.1063/1.3678304en
dc.identifier.urihttp://hdl.handle.net/10754/552839en
dc.description.abstractThe general working principle of magnetoresistive sensors for biological applications is to specifically attach bioanalytesto magnetic particles and then detect the particles that are immobilized on the sensor surface. The immobilization of the particles on the sensor surface commonly uses biomolecular interactions, e.g., antigen-antibody. Thus, the sensor surface needs to be functionalized via biological treatments in order to capture certain bioanalytes. In the presented work, a new method is proposed, which does not rely on functionalization of the sensor surface. Current carrying microstructures in combination with mechanical micro traps are used to immobilize magnetic particles. Analyte detection is based on the difference in size between bare magnetic particles and particles with analyte attached, which causes a different number of particles to be captured in the micro traps.en
dc.relation.urlhttp://scitation.aip.org/content/aip/journal/jap/111/7/10.1063/1.3678304en
dc.rightsArchived with thanks to Journal of Applied Physicsen
dc.titleA biodetection method using magnetic particles and micro trapsen
dc.typeArticleen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.identifier.journalJournal of Applied Physicsen
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionInstitute of Sensor and Actuator Systems, Vienna University of Technology, 1040 Vienna, Austriaen
kaust.authorKosel, Jürgenen
kaust.authorLi, Fuquanen
All Items in KAUST are protected by copyright, with all rights reserved, unless otherwise indicated.