A magnetic particle micro-trap for large trapping surfaces

Handle URI:
http://hdl.handle.net/10754/552531
Title:
A magnetic particle micro-trap for large trapping surfaces
Authors:
Gooneratne, Chinthaka P.; Liang, Cai ( 0000-0002-5844-3432 ) ; Giouroudi, Ioanna; Kosel, Jürgen ( 0000-0002-8998-8275 )
Abstract:
Manipulation of micron-size magnetic particles of the superparamagnetic type contributes significantly in many applications like controlling the antibody/antigen binding process in immunoassays. Specifically, more target biomolecules can be attached/tagged and analyzed since the three dimensional structure of the magnetic particles increases the surface to volume ratio. Additionally, such biomolecular-tagged magnetic particles can be easily manipulated by an external magnetic field due to their superparamagnetic behavior. Therefore, magnetic particle- based immunoassays are extensively applied in micro-flow cytometry. The design of a square-loop micro-trap as a magnetic particle manipulator as well as numerical and experimental analysis is presented. Experimental results showed that the micro-trap could successfully trap and concentrate magnetic particles from a large to a small area with a high spatial range.
KAUST Department:
Physical Sciences and Engineering (PSE) Division
Citation:
A magnetic particle micro-trap for large trapping surfaces 2011, 25:1201 Procedia Engineering
Journal:
Procedia Engineering
Issue Date:
8-Jan-2012
DOI:
10.1016/j.proeng.2011.12.296
Type:
Article
ISSN:
18777058
Additional Links:
http://linkinghub.elsevier.com/retrieve/pii/S1877705811059650
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorGooneratne, Chinthaka P.en
dc.contributor.authorLiang, Caien
dc.contributor.authorGiouroudi, Ioannaen
dc.contributor.authorKosel, Jürgenen
dc.date.accessioned2015-05-10T14:28:51Zen
dc.date.available2015-05-10T14:28:51Zen
dc.date.issued2012-01-08en
dc.identifier.citationA magnetic particle micro-trap for large trapping surfaces 2011, 25:1201 Procedia Engineeringen
dc.identifier.issn18777058en
dc.identifier.doi10.1016/j.proeng.2011.12.296en
dc.identifier.urihttp://hdl.handle.net/10754/552531en
dc.description.abstractManipulation of micron-size magnetic particles of the superparamagnetic type contributes significantly in many applications like controlling the antibody/antigen binding process in immunoassays. Specifically, more target biomolecules can be attached/tagged and analyzed since the three dimensional structure of the magnetic particles increases the surface to volume ratio. Additionally, such biomolecular-tagged magnetic particles can be easily manipulated by an external magnetic field due to their superparamagnetic behavior. Therefore, magnetic particle- based immunoassays are extensively applied in micro-flow cytometry. The design of a square-loop micro-trap as a magnetic particle manipulator as well as numerical and experimental analysis is presented. Experimental results showed that the micro-trap could successfully trap and concentrate magnetic particles from a large to a small area with a high spatial range.en
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S1877705811059650en
dc.rightsArchived with thanks to Procedia Engineering. http://creativecommons.org/licenses/by-nc-nd/3.0/en
dc.subjectmagnetic particleen
dc.subjectmicro-trapen
dc.subjectcytometryen
dc.titleA magnetic particle micro-trap for large trapping surfacesen
dc.typeArticleen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.identifier.journalProcedia Engineeringen
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionInstitute of Sensor and Actuator Systems, Vienna University of Technoloy, Gusshausstrasse 27-29/366-ISS, Vienna, 1040, Austriaen
kaust.authorGooneratne, Chinthaka Pasanen
kaust.authorLiang, Caien
kaust.authorKosel, Jürgenen
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