Analysis of some pharmaceuticals in municipal wastewater of Almadinah Almunawarah

Handle URI:
http://hdl.handle.net/10754/552455
Title:
Analysis of some pharmaceuticals in municipal wastewater of Almadinah Almunawarah
Authors:
Shraim, Amjad; Diab, Atef; Alsuhaimi, Awadh; Niazy, Esmail; Metwally, Mohammed; Amad, Maan H.; Sioud, Salim; Dawoud, Abdulilah
Abstract:
The chemical pollution of water resources is a major challenge facing the humanity in this century. Pharmaceuticals and personal care products (PPCPs) are a group of emerging environmental chemical pollutants distinguished by their bioactivity and high solubility. They may also cause health complications to humans and living organisms. Pharmaceuticals enter the environment, mainly via wastewater and can eventually reach the surface and ground water. Despite this, PPCPs received less attention as environmental pollutants than other chemical pollutants (e.g. heavy metals and pesticides). The purpose of this work was to investigate the presence of some of the most frequently dispensed drugs for the residents of Almadinah Almunawarah, Saudi Arabia in the municipal wastewater before and after treatment. For this purpose, wastewater samples were collected biweekly from the city’s sewage treatment plant for a period of 4 months and analyzed the targeted drugs using tandem LC–MS. Out of the 19 investigated drugs, 5 pharmaceuticals have been found in concentrations greater than the limit of detection in both the influents and effluents of the sewage treatment plant. As expected, the concentrations of investigated pharmaceuticals in the wastewater were found to be low. These drugs and their average concentrations (in ng mL−1) in the influents were: acetaminophen (38.9), metformin (15.2), norfluoxetine (7.07), atenolol (2.04), and cephalexin (1.88). Meanwhile, the effluents contained slightly lower levels (in ng mL−1) than those of influents: acetaminophen (31.2), metformin (3.19), norfluoxetine (7.25), atenolol (0.545), and cephalexin (1.53). The results of this study supported by many other investigations indicate the inefficiency of current conventional wastewater treatment protocols in eliminating such a group of active and potentially hazardous pollutants from the wastewater.
KAUST Department:
Analytical Core Lab
Citation:
Analysis of some pharmaceuticals in municipal wastewater of Almadinah Almunawarah 2012 Arabian Journal of Chemistry
Journal:
Arabian Journal of Chemistry
Issue Date:
29-Nov-2012
DOI:
10.1016/j.arabjc.2012.11.014
Type:
Article
ISSN:
18785352
Additional Links:
http://linkinghub.elsevier.com/retrieve/pii/S1878535212002705
Appears in Collections:
Articles; Analytical Core Lab

Full metadata record

DC FieldValue Language
dc.contributor.authorShraim, Amjaden
dc.contributor.authorDiab, Atefen
dc.contributor.authorAlsuhaimi, Awadhen
dc.contributor.authorNiazy, Esmailen
dc.contributor.authorMetwally, Mohammeden
dc.contributor.authorAmad, Maan H.en
dc.contributor.authorSioud, Salimen
dc.contributor.authorDawoud, Abdulilahen
dc.date.accessioned2015-05-07T13:53:16Zen
dc.date.available2015-05-07T13:53:16Zen
dc.date.issued2012-11-29en
dc.identifier.citationAnalysis of some pharmaceuticals in municipal wastewater of Almadinah Almunawarah 2012 Arabian Journal of Chemistryen
dc.identifier.issn18785352en
dc.identifier.doi10.1016/j.arabjc.2012.11.014en
dc.identifier.urihttp://hdl.handle.net/10754/552455en
dc.description.abstractThe chemical pollution of water resources is a major challenge facing the humanity in this century. Pharmaceuticals and personal care products (PPCPs) are a group of emerging environmental chemical pollutants distinguished by their bioactivity and high solubility. They may also cause health complications to humans and living organisms. Pharmaceuticals enter the environment, mainly via wastewater and can eventually reach the surface and ground water. Despite this, PPCPs received less attention as environmental pollutants than other chemical pollutants (e.g. heavy metals and pesticides). The purpose of this work was to investigate the presence of some of the most frequently dispensed drugs for the residents of Almadinah Almunawarah, Saudi Arabia in the municipal wastewater before and after treatment. For this purpose, wastewater samples were collected biweekly from the city’s sewage treatment plant for a period of 4 months and analyzed the targeted drugs using tandem LC–MS. Out of the 19 investigated drugs, 5 pharmaceuticals have been found in concentrations greater than the limit of detection in both the influents and effluents of the sewage treatment plant. As expected, the concentrations of investigated pharmaceuticals in the wastewater were found to be low. These drugs and their average concentrations (in ng mL−1) in the influents were: acetaminophen (38.9), metformin (15.2), norfluoxetine (7.07), atenolol (2.04), and cephalexin (1.88). Meanwhile, the effluents contained slightly lower levels (in ng mL−1) than those of influents: acetaminophen (31.2), metformin (3.19), norfluoxetine (7.25), atenolol (0.545), and cephalexin (1.53). The results of this study supported by many other investigations indicate the inefficiency of current conventional wastewater treatment protocols in eliminating such a group of active and potentially hazardous pollutants from the wastewater.en
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S1878535212002705en
dc.rightsArchived with thanks to Arabian Journal of Chemistry. http://creativecommons.org/licenses/by-nc-nd/3.0/en
dc.subjectWastewater treatmenten
dc.subjectAntibioticsen
dc.subjectEmerging environmental pollutantsen
dc.subjectFrequently dispensed drugsen
dc.subjectSaudi Arabiaen
dc.subjectTandem LC–MSen
dc.titleAnalysis of some pharmaceuticals in municipal wastewater of Almadinah Almunawarahen
dc.typeArticleen
dc.contributor.departmentAnalytical Core Laben
dc.identifier.journalArabian Journal of Chemistryen
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionChemistry Department, Faculty of Science, Taibah University, Almadinah Almunawarah, Saudi Arabiaen
dc.contributor.institutionToxicological Research and Studies Centre, Taibah University, Almadinah Almunawarah, Saudi Arabiaen
dc.contributor.institutionThe University of Queensland, National Research Centre for Environmental Toxicology (Entox), Brisbane, Queensland, Australiaen
dc.contributor.institutionDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Taibah University, Almadinah Almunawarah, Saudi Arabiaen
dc.contributor.institutionCollege of Pharmacy, Taibah University, Almadinah Almunawarah, Saudi Arabiaen
kaust.authorAmad, Maan H.en
kaust.authorSioud, Salimen
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