A red and far-red light receptor mutation confers resistance to the herbicide glyphosate

Handle URI:
http://hdl.handle.net/10754/550789
Title:
A red and far-red light receptor mutation confers resistance to the herbicide glyphosate
Authors:
Sharkhuu, Altanbadralt ( 0000-0002-4719-0265 ) ; Narasimhan, Meena L.; Merzaban, Jasmeen S. ( 0000-0002-7276-2907 ) ; Bressan, Ray A.; Weller, Steve; Gehring, Christoph A. ( 0000-0003-4355-4591 )
Abstract:
Glyphosate is a widely applied broad-spectrum systemic herbicide that inhibits competitively the penultimate enzyme 5-enolpyruvylshikimate 3-phosphate synthase (EPSPS) from the shikimate pathway, thereby causing deleterious effects. A glyphosate-resistant Arabidopsis mutant (gre1) was isolated and genetic analyses indicated that a dysfunctional red (R) and far-red (FR) light receptor, phytochrome B (phyB), caused this phenotype. This finding is consistent with increased glyphosate sensitivity and glyphosate-induced shikimate accumulation in low R:FR light, and the induction of genes encoding enzymes of the shikimate pathway in high R:FR light. Expression of the shikimate pathway genes exhibited diurnal oscillation and this oscillation was altered in the phyB mutant. Furthermore, transcript analysis suggested that this diurnal oscillation was not only dependent on phyB but was also due to circadian regulatory mechanisms. Our data offer an explanation of the well documented observation that glyphosate treatment at various times throughout the day, with their specific composition of light quality and intensity, results in different efficiencies of the herbicide.
KAUST Department:
Biological and Environmental Sciences and Engineering (BESE) Division
Citation:
A red and far-red light receptor mutation confers resistance to the herbicide glyphosate 2014, 78 (6):916 The Plant Journal
Publisher:
Wiley-Blackwell
Journal:
The Plant Journal
Issue Date:
Jun-2014
DOI:
10.1111/tpj.12513
PubMed ID:
24654847
PubMed Central ID:
PMC4260087
Type:
Article
ISSN:
09607412
Additional Links:
http://doi.wiley.com/10.1111/tpj.12513
Appears in Collections:
Articles; Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorSharkhuu, Altanbadralten
dc.contributor.authorNarasimhan, Meena L.en
dc.contributor.authorMerzaban, Jasmeen S.en
dc.contributor.authorBressan, Ray A.en
dc.contributor.authorWeller, Steveen
dc.contributor.authorGehring, Christoph A.en
dc.date.accessioned2015-04-28T08:48:47Zen
dc.date.available2015-04-28T08:48:47Zen
dc.date.issued2014-06en
dc.identifier.citationA red and far-red light receptor mutation confers resistance to the herbicide glyphosate 2014, 78 (6):916 The Plant Journalen
dc.identifier.issn09607412en
dc.identifier.pmid24654847en
dc.identifier.doi10.1111/tpj.12513en
dc.identifier.urihttp://hdl.handle.net/10754/550789en
dc.description.abstractGlyphosate is a widely applied broad-spectrum systemic herbicide that inhibits competitively the penultimate enzyme 5-enolpyruvylshikimate 3-phosphate synthase (EPSPS) from the shikimate pathway, thereby causing deleterious effects. A glyphosate-resistant Arabidopsis mutant (gre1) was isolated and genetic analyses indicated that a dysfunctional red (R) and far-red (FR) light receptor, phytochrome B (phyB), caused this phenotype. This finding is consistent with increased glyphosate sensitivity and glyphosate-induced shikimate accumulation in low R:FR light, and the induction of genes encoding enzymes of the shikimate pathway in high R:FR light. Expression of the shikimate pathway genes exhibited diurnal oscillation and this oscillation was altered in the phyB mutant. Furthermore, transcript analysis suggested that this diurnal oscillation was not only dependent on phyB but was also due to circadian regulatory mechanisms. Our data offer an explanation of the well documented observation that glyphosate treatment at various times throughout the day, with their specific composition of light quality and intensity, results in different efficiencies of the herbicide.en
dc.publisherWiley-Blackwellen
dc.relation.urlhttp://doi.wiley.com/10.1111/tpj.12513en
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.en
dc.subjectArabidopsis thalianaen
dc.subjectglyphosateen
dc.subjectherbicide resistanceen
dc.subjectshikimate pathwayen
dc.subjectphyBen
dc.subjectcircadian rhythmen
dc.titleA red and far-red light receptor mutation confers resistance to the herbicide glyphosateen
dc.typeArticleen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.identifier.journalThe Plant Journalen
dc.identifier.pmcidPMC4260087en
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionDepartment of Horticulture and Landscape Architecture; Purdue University; 47907 West Lafayette Indiana USAen
dc.contributor.institutionDepartment of Horticulture and Landscape Architecture; Purdue University; 47907 West Lafayette Indiana USAen
kaust.authorSharkhuu, Altanbadralten
kaust.authorMerzaban, Jasmeen S.en
kaust.authorBressan, Ray Anthonyen
kaust.authorGehring, Christoph A.en

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