Design and fabrication of magnetically functionalized flexible micropillar arrays for rapid and controllable microfluidic mixing

Handle URI:
http://hdl.handle.net/10754/347341
Title:
Design and fabrication of magnetically functionalized flexible micropillar arrays for rapid and controllable microfluidic mixing
Authors:
Zhou, BingPu; Xu, Wei; Syed, Ahad; Chau, Yeungyeung; Chen, Longqing; Chew, Basil; Yassine, Omar ( 0000-0002-0117-8017 ) ; Wu, Xiaoxiao; Gao, Yibo; Zhang, Jingxian; Xiao, Xiao; Kosel, Jürgen ( 0000-0002-8998-8275 ) ; Zhang, Xixiang ( 0000-0002-3478-6414 ) ; Yao, Zhaohui; Wen, Weijia
Abstract:
Magnetically functionalized PDMS-based micropillar arrays have been successfully designed, fabricated and implanted for controllable microfluidic mixing. The arrangement of PDMS micropillar arrays inside the microchannel can be flexibly controlled by an external magnetic field. As a consequence, the flow fields inside the microchannel can be regulated at will via magnetic activation conveniently. When a microchannel is implanted with such micropillar arrays, two microstreams can be mixed easily and controllably upon the simple application of an on/off magnetic signal. Mixing efficiencies based on micropillar arrays with different densities were investigated and compared. It was found that micropillar arrays with higher density (i.e. smaller pillar pitch) would render better mixing performance. Our microfluidic system is capable of generating highly reproducible results within many cycles of mixing/non-mixing conversion. We believe that the simple mixing-triggering method together with rapid and controllable mixing control will be extraordinarily valuable for various biological or chemical applications in the future. This journal is © The Royal Society of Chemistry 2015.
KAUST Department:
KAUST-HKUST Micro/Nanofluidic Joint Laboratory; Advanced Nanofabrication, Imaging and Characterization Core Lab; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Citation:
Design and fabrication of magnetically functionalized flexible micropillar arrays for rapid and controllable microfluidic mixing 2015 Lab Chip
Publisher:
Royal Society of Chemistry (RSC)
Journal:
Lab Chip
Issue Date:
25-Mar-2015
DOI:
10.1039/C5LC00173K
Type:
Article
ISSN:
1473-0197; 1473-0189
Additional Links:
http://pubs.rsc.org/en/Content/ArticleLanding/2015/LC/C5LC00173K
Appears in Collections:
Articles; Advanced Nanofabrication, Imaging and Characterization Core Lab; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorZhou, BingPuen
dc.contributor.authorXu, Weien
dc.contributor.authorSyed, Ahaden
dc.contributor.authorChau, Yeungyeungen
dc.contributor.authorChen, Longqingen
dc.contributor.authorChew, Basilen
dc.contributor.authorYassine, Omaren
dc.contributor.authorWu, Xiaoxiaoen
dc.contributor.authorGao, Yiboen
dc.contributor.authorZhang, Jingxianen
dc.contributor.authorXiao, Xiaoen
dc.contributor.authorKosel, Jürgenen
dc.contributor.authorZhang, Xixiangen
dc.contributor.authorYao, Zhaohuien
dc.contributor.authorWen, Weijiaen
dc.date.accessioned2015-03-31T06:23:28Zen
dc.date.available2015-03-31T06:23:28Zen
dc.date.issued2015-03-25en
dc.identifier.citationDesign and fabrication of magnetically functionalized flexible micropillar arrays for rapid and controllable microfluidic mixing 2015 Lab Chipen
dc.identifier.issn1473-0197en
dc.identifier.issn1473-0189en
dc.identifier.doi10.1039/C5LC00173Ken
dc.identifier.urihttp://hdl.handle.net/10754/347341en
dc.description.abstractMagnetically functionalized PDMS-based micropillar arrays have been successfully designed, fabricated and implanted for controllable microfluidic mixing. The arrangement of PDMS micropillar arrays inside the microchannel can be flexibly controlled by an external magnetic field. As a consequence, the flow fields inside the microchannel can be regulated at will via magnetic activation conveniently. When a microchannel is implanted with such micropillar arrays, two microstreams can be mixed easily and controllably upon the simple application of an on/off magnetic signal. Mixing efficiencies based on micropillar arrays with different densities were investigated and compared. It was found that micropillar arrays with higher density (i.e. smaller pillar pitch) would render better mixing performance. Our microfluidic system is capable of generating highly reproducible results within many cycles of mixing/non-mixing conversion. We believe that the simple mixing-triggering method together with rapid and controllable mixing control will be extraordinarily valuable for various biological or chemical applications in the future. This journal is © The Royal Society of Chemistry 2015.en
dc.publisherRoyal Society of Chemistry (RSC)en
dc.relation.urlhttp://pubs.rsc.org/en/Content/ArticleLanding/2015/LC/C5LC00173Ken
dc.rightsArchived with thanks to Lab Chip. © Royal Society of Chemistry 2015en
dc.titleDesign and fabrication of magnetically functionalized flexible micropillar arrays for rapid and controllable microfluidic mixingen
dc.typeArticleen
dc.contributor.departmentKAUST-HKUST Micro/Nanofluidic Joint Laboratoryen
dc.contributor.departmentAdvanced Nanofabrication, Imaging and Characterization Core Laben
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Divisionen
dc.identifier.journalLab Chipen
dc.eprint.versionPost-printen
dc.contributor.institutionNano Science and Technology Program, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kongen
dc.contributor.institutionDepartment of Physics, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kongen
dc.contributor.institutionDepartment of Engineering Mechanics, Tsinghua University, Beijing, P. R. Chinaen
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)en
kaust.authorChen, Longqingen
kaust.authorYassine, Omaren
kaust.authorKosel, Jürgenen
kaust.authorZhang, Xixiangen
kaust.authorXu, Weien
kaust.authorSyed, Ahad A.en
kaust.authorChew, Basilen
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