The Effect of Multiple Paternity on Genetic Diversity of Small Populations during and after Colonisation

Handle URI:
http://hdl.handle.net/10754/325326
Title:
The Effect of Multiple Paternity on Genetic Diversity of Small Populations during and after Colonisation
Authors:
Rafajlović, Marina; Eriksson, Anders ( 0000-0003-3436-3726 ) ; Rimark, Anna; Hintz-Saltin, Sara; Charrier, Grégory; Panova, Marina; André, Carl; Johannesson, Kerstin; Mehlig, Bernhard
Abstract:
Genetic variation within and among populations is influenced by the genetic content of the founders and the migrants following establishment. This is particularly true if populations are small, migration rate low and habitats arranged in a stepping-stone fashion. Under these circumstances the level of multiple paternity is critical since multiply mated females bring more genetic variation into founder groups than single mated females. One such example is the marine snail Littorina saxatilis that during postglacial times has invaded mainland refuge areas and thereafter small islands emerging due to isostatic uplift by occasional rafting of multiply mated females. We modelled effects of varying degrees of multiple paternity on the genetic variation of island populations colonised by the founders spreading from the mainland, by quantifying the population heterozygosity during both the transient colonisation process, and after a steady state (with migration) has been reached. During colonisation, multiple mating by 2-10 males increased the heterozygosity by 10-300% in comparison with single paternity, while in the steady state the increase was 10-50% compared with single paternity. In the steady state the increase of heterozygosity due to multiple paternity is determined by a corresponding increase in effective population size. During colonisation, by contrast, the increase in heterozygosity is larger and it cannot be explained in terms of the effective population size alone. During the steady-state phase bursts of high genetic variation spread through the system, and far from the mainland this led to short periods of high diversity separated by long periods of low diversity. The size of these fluctuations was boosted by multiple paternity. We conclude that following glacial periods of extirpation, recolonization of isolated habitats by this species has been supported by its high level of multiple paternity. 2013 Rafajlovi? et al.
Citation:
Rafajlović M, Eriksson A, Rimark A, Hintz-Saltin S, Charrier G, et al. (2013) The Effect of Multiple Paternity on Genetic Diversity of Small Populations during and after Colonisation. PLoS ONE 8: e75587. doi:10.1371/journal.pone.0075587.
Publisher:
Public Library of Science
Journal:
PLoS ONE
Issue Date:
28-Oct-2013
DOI:
10.1371/journal.pone.0075587
PubMed ID:
24204577
PubMed Central ID:
PMC3810386
ARXIV:
arXiv:1211.0937
Type:
Article
ISSN:
19326203
Additional Links:
http://arxiv.org/abs/1211.0937
Appears in Collections:
Articles; Integrative Systems Biology Lab

Full metadata record

DC FieldValue Language
dc.contributor.authorRafajlović, Marinaen
dc.contributor.authorEriksson, Andersen
dc.contributor.authorRimark, Annaen
dc.contributor.authorHintz-Saltin, Saraen
dc.contributor.authorCharrier, Grégoryen
dc.contributor.authorPanova, Marinaen
dc.contributor.authorAndré, Carlen
dc.contributor.authorJohannesson, Kerstinen
dc.contributor.authorMehlig, Bernharden
dc.date.accessioned2014-08-27T09:47:06Zen
dc.date.available2014-08-27T09:47:06Zen
dc.date.issued2013-10-28en
dc.identifier.citationRafajlović M, Eriksson A, Rimark A, Hintz-Saltin S, Charrier G, et al. (2013) The Effect of Multiple Paternity on Genetic Diversity of Small Populations during and after Colonisation. PLoS ONE 8: e75587. doi:10.1371/journal.pone.0075587.en
dc.identifier.issn19326203en
dc.identifier.pmid24204577en
dc.identifier.doi10.1371/journal.pone.0075587en
dc.identifier.urihttp://hdl.handle.net/10754/325326en
dc.description.abstractGenetic variation within and among populations is influenced by the genetic content of the founders and the migrants following establishment. This is particularly true if populations are small, migration rate low and habitats arranged in a stepping-stone fashion. Under these circumstances the level of multiple paternity is critical since multiply mated females bring more genetic variation into founder groups than single mated females. One such example is the marine snail Littorina saxatilis that during postglacial times has invaded mainland refuge areas and thereafter small islands emerging due to isostatic uplift by occasional rafting of multiply mated females. We modelled effects of varying degrees of multiple paternity on the genetic variation of island populations colonised by the founders spreading from the mainland, by quantifying the population heterozygosity during both the transient colonisation process, and after a steady state (with migration) has been reached. During colonisation, multiple mating by 2-10 males increased the heterozygosity by 10-300% in comparison with single paternity, while in the steady state the increase was 10-50% compared with single paternity. In the steady state the increase of heterozygosity due to multiple paternity is determined by a corresponding increase in effective population size. During colonisation, by contrast, the increase in heterozygosity is larger and it cannot be explained in terms of the effective population size alone. During the steady-state phase bursts of high genetic variation spread through the system, and far from the mainland this led to short periods of high diversity separated by long periods of low diversity. The size of these fluctuations was boosted by multiple paternity. We conclude that following glacial periods of extirpation, recolonization of isolated habitats by this species has been supported by its high level of multiple paternity. 2013 Rafajlovi? et al.en
dc.language.isoenen
dc.publisherPublic Library of Scienceen
dc.relation.urlhttp://arxiv.org/abs/1211.0937en
dc.rightsThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en
dc.rightsArchived with thanks to PLoS ONEen
dc.subjectanimal experimenten
dc.subjectcontrolled studyen
dc.subjecteffective population sizeen
dc.subjectgenetic variabilityen
dc.subjectheterozygosityen
dc.subjectLittorinaen
dc.subjectLittorina saxatilisen
dc.subjectmating successen
dc.subjectmating typeen
dc.subjectmutational analysisen
dc.subjectpaternityen
dc.subjectpopulation distributionen
dc.subjectpopulation genetic structureen
dc.subjectpopulation growthen
dc.subjectsimulationen
dc.subjectspecies habitaten
dc.subjectsteady stateen
dc.titleThe Effect of Multiple Paternity on Genetic Diversity of Small Populations during and after Colonisationen
dc.typeArticleen
dc.identifier.journalPLoS ONEen
dc.identifier.pmcidPMC3810386en
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionDepartment of Physics, University of Gothenburg, Gothenburg, Swedenen
dc.contributor.institutionDepartment of Zoology, University of Cambridge, Cambridge, United Kingdomen
dc.contributor.institutionDepartment of Biological and Environmental Sciences-Tjrn, University of Gothenburg, Strmstad, Swedenen
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)en
dc.identifier.arxividarXiv:1211.0937en
kaust.authorEriksson, Andersen
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