Determination of nanoparticle size distribution together with density or molecular weight by 2D analytical ultracentrifugation

Handle URI:
http://hdl.handle.net/10754/325302
Title:
Determination of nanoparticle size distribution together with density or molecular weight by 2D analytical ultracentrifugation
Authors:
Carney, Randy P.; Kim, Jin Young; Qian, Huifeng; Jin, Rongchao; Mehenni, Hakim; Stellacci, Francesco; Bakr, Osman M. ( 0000-0002-3428-1002 )
Abstract:
Nanoparticles are finding many research and industrial applications, yet their characterization remains a challenge. Their cores are often polydisperse and coated by a stabilizing shell that varies in size and composition. No single technique can characterize both the size distribution and the nature of the shell. Advances in analytical ultracentrifugation allow for the extraction of the sedimentation (s) and diffusion coefficients (D). Here we report an approach to transform the s and D distributions of nanoparticles in solution into precise molecular weight (M), density (?P) and particle diameter (dp) distributions. M for mixtures of discrete nanocrystals is found within 4% of the known quantities. The accuracy and the density information we achieve on nanoparticles are unparalleled. A single experimental run is sufficient for full nanoparticle characterization, without the need for standards or other auxiliary measurements. We believe that our method is of general applicability and we discuss its limitations. 2011 Macmillan Publishers Limited. All rights reserved.
KAUST Department:
Solar and Photovoltaic Engineering Research Center; Physical Sciences and Engineering (PSE) Division
Citation:
Carney RP, Kim JY, Qian H, Jin R, Mehenni H, et al. (2011) Determination of nanoparticle size distribution together with density or molecular weight by 2D analytical ultracentrifugation. Nature Communications 2: 335. doi:10.1038/ncomms1338.
Publisher:
Springer Nature
Journal:
Nature Communications
Issue Date:
7-Jun-2011
DOI:
10.1038/ncomms1338
PubMed ID:
21654635
PubMed Central ID:
PMC3158653
Type:
Article
ISSN:
20411723
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; Solar and Photovoltaic Engineering Research Center (SPERC)

Full metadata record

DC FieldValue Language
dc.contributor.authorCarney, Randy P.en
dc.contributor.authorKim, Jin Youngen
dc.contributor.authorQian, Huifengen
dc.contributor.authorJin, Rongchaoen
dc.contributor.authorMehenni, Hakimen
dc.contributor.authorStellacci, Francescoen
dc.contributor.authorBakr, Osman M.en
dc.date.accessioned2014-08-27T09:45:55Z-
dc.date.available2014-08-27T09:45:55Z-
dc.date.issued2011-06-07en
dc.identifier.citationCarney RP, Kim JY, Qian H, Jin R, Mehenni H, et al. (2011) Determination of nanoparticle size distribution together with density or molecular weight by 2D analytical ultracentrifugation. Nature Communications 2: 335. doi:10.1038/ncomms1338.en
dc.identifier.issn20411723en
dc.identifier.pmid21654635en
dc.identifier.doi10.1038/ncomms1338en
dc.identifier.urihttp://hdl.handle.net/10754/325302en
dc.description.abstractNanoparticles are finding many research and industrial applications, yet their characterization remains a challenge. Their cores are often polydisperse and coated by a stabilizing shell that varies in size and composition. No single technique can characterize both the size distribution and the nature of the shell. Advances in analytical ultracentrifugation allow for the extraction of the sedimentation (s) and diffusion coefficients (D). Here we report an approach to transform the s and D distributions of nanoparticles in solution into precise molecular weight (M), density (?P) and particle diameter (dp) distributions. M for mixtures of discrete nanocrystals is found within 4% of the known quantities. The accuracy and the density information we achieve on nanoparticles are unparalleled. A single experimental run is sufficient for full nanoparticle characterization, without the need for standards or other auxiliary measurements. We believe that our method is of general applicability and we discuss its limitations. 2011 Macmillan Publishers Limited. All rights reserved.en
dc.language.isoenen
dc.publisherSpringer Natureen
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/en
dc.subjectnanocrystalen
dc.subjectnanoparticleen
dc.subjectgolden
dc.subjectnanoparticleen
dc.subjectaccuracyen
dc.subjectanalytic methoden
dc.subjectdiffusion coefficienten
dc.subjectextractionen
dc.subjectmeasurementen
dc.subjectmolecular weighten
dc.subjectsedimentationen
dc.subjectultracentrifugationen
dc.subjectarea under the curveen
dc.subjectchemical modelen
dc.subjectchemistryen
dc.subjectmethodologyen
dc.subjectmolecular weighten
dc.subjectparticle sizeen
dc.subjectthermodynamicsen
dc.subjecttransmission electron microscopyen
dc.subjectArea Under Curveen
dc.subjectGolden
dc.subjectMicroscopy, Electron, Transmissionen
dc.subjectModels, Chemicalen
dc.subjectMolecular Weighten
dc.subjectNanoparticlesen
dc.subjectParticle Sizeen
dc.subjectThermodynamicsen
dc.subjectUltracentrifugationen
dc.titleDetermination of nanoparticle size distribution together with density or molecular weight by 2D analytical ultracentrifugationen
dc.typeArticleen
dc.contributor.departmentSolar and Photovoltaic Engineering Research Centeren
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.identifier.journalNature Communicationsen
dc.identifier.pmcidPMC3158653en
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United Statesen
dc.contributor.institutionInstitute of Materials, cole Polytechnique Fdrale de Lausanne, Station 12, 1015 Lausanne, Switzerlanden
dc.contributor.institutionDepartment of Chemistry, Carnegie Melon University, Pittsburgh, PA 15213, United Statesen
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)en
kaust.authorMehenni, Hakimen
kaust.authorBakr, Osman M.en
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