Induction of apoptosis in cancer cell lines by the Red Sea brine pool bacterial extracts.

Handle URI:
http://hdl.handle.net/10754/323527
Title:
Induction of apoptosis in cancer cell lines by the Red Sea brine pool bacterial extracts.
Authors:
Sagar, Sunil; Esau, Luke; Holtermann, Karie; Hikmawan, Tyas I. ( 0000-0001-7239-3374 ) ; Zhang, Guishan; Stingl, Ulrich ( 0000-0002-0684-2597 ) ; Bajic, Vladimir B. ( 0000-0001-5435-4750 ) ; Kaur, Mandeep
Abstract:
Marine microorganisms are considered to be an important source of bioactive molecules against various diseases and have great potential to increase the number of lead molecules in clinical trials. Progress in novel microbial culturing techniques as well as greater accessibility to unique oceanic habitats has placed the marine environment as a new frontier in the field of natural product drug discovery.
KAUST Department:
Red Sea Research Center (RSRC)
Citation:
Sagar S, Esau L, Holtermann K, Hikmawan T, Zhang G, et al. (2013) Induction of apoptosis in cancer cell lines by the Red Sea brine pool bacterial extracts. BMC Complementary and Alternative Medicine 13: 344. doi:10.1186/1472-6882-13-344.
Publisher:
Biomed Central
Journal:
BMC complementary and alternative medicine
Issue Date:
5-Dec-2013
DOI:
10.1186/1472-6882-13-344
PubMed ID:
24305113
PubMed Central ID:
PMC4235048
Type:
Article
ISSN:
1472-6882
Additional Links:
http://www.biomedcentral.com/1472-6882/13/344/
Appears in Collections:
Articles; Red Sea Research Center (RSRC)

Full metadata record

DC FieldValue Language
dc.contributor.authorSagar, Sunilen
dc.contributor.authorEsau, Lukeen
dc.contributor.authorHoltermann, Karieen
dc.contributor.authorHikmawan, Tyas I.en
dc.contributor.authorZhang, Guishanen
dc.contributor.authorStingl, Ulrichen
dc.contributor.authorBajic, Vladimir B.en
dc.contributor.authorKaur, Mandeepen
dc.date.accessioned2014-07-21T10:34:26Z-
dc.date.available2014-07-21T10:34:26Z-
dc.date.issued2013-12-05en
dc.identifier.citationSagar S, Esau L, Holtermann K, Hikmawan T, Zhang G, et al. (2013) Induction of apoptosis in cancer cell lines by the Red Sea brine pool bacterial extracts. BMC Complementary and Alternative Medicine 13: 344. doi:10.1186/1472-6882-13-344.en
dc.identifier.issn1472-6882en
dc.identifier.pmid24305113en
dc.identifier.doi10.1186/1472-6882-13-344en
dc.identifier.urihttp://hdl.handle.net/10754/323527en
dc.description.abstractMarine microorganisms are considered to be an important source of bioactive molecules against various diseases and have great potential to increase the number of lead molecules in clinical trials. Progress in novel microbial culturing techniques as well as greater accessibility to unique oceanic habitats has placed the marine environment as a new frontier in the field of natural product drug discovery.en
dc.language.isoenen
dc.publisherBiomed Centralen
dc.relation.urlhttp://www.biomedcentral.com/1472-6882/13/344/en
dc.rightsArchived with thanks to BMC complementary and alternative medicineen
dc.subject.meshAntineoplastic Agentsen
dc.subject.meshApoptosisen
dc.subject.meshAquatic Organismsen
dc.subject.meshBiological Productsen
dc.subject.meshCaspasesen
dc.subject.meshCell Line, Tumoren
dc.subject.meshCell Proliferationen
dc.subject.meshFlow Cytometryen
dc.subject.meshHalomonadaceaeen
dc.subject.meshHistonesen
dc.subject.meshHumansen
dc.subject.meshIndian Oceanen
dc.subject.meshMembrane Potential, Mitochondrialen
dc.subject.meshPoly(ADP-ribose) Polymerasesen
dc.subject.meshWater Microbiologyen
dc.subject.meshAntineoplastic Agentsen
dc.subject.meshApoptosisen
dc.subject.meshAquatic Organismsen
dc.subject.meshBiological Productsen
dc.subject.meshCaspasesen
dc.subject.meshCell Line, Tumoren
dc.subject.meshCell Proliferationen
dc.subject.meshFlow Cytometryen
dc.subject.meshHalomonadaceaeen
dc.subject.meshHistonesen
dc.subject.meshHumansen
dc.subject.meshIndian Oceanen
dc.subject.meshMembrane Potential, Mitochondrialen
dc.subject.meshPoly(ADP-ribose) Polymerasesen
dc.subject.meshWater Microbiologyen
dc.titleInduction of apoptosis in cancer cell lines by the Red Sea brine pool bacterial extracts.en
dc.typeArticleen
dc.contributor.departmentRed Sea Research Center (RSRC)en
dc.identifier.journalBMC complementary and alternative medicineen
dc.identifier.pmcidPMC4235048en
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionBiotechnology Graduate Program, American University in Cairo, Cairo, Egypten
dc.contributor.institutionDepartment of Biology, American University in Cairo, Cairo, Egypten
dc.contributor.institutionThe Science and Technology Research Center, American University in Cairo, Cairo, Egypten
dc.contributor.institutionDepartment of Chemistry, American University in Cairo, Cairo, Egypten
dc.contributor.institutionMarine Chemistry and Geochemistry Department, Woods Hole Oceanographic Institution, Woods Hole, MA, United Statesen
dc.contributor.institutionJosephine Bay Paul Center, Marine Biological Laboratory, Woods Hole, MA, United Statesen
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)en
kaust.authorSagar, Sunilen
kaust.authorEsau, Lukeen
kaust.authorHoltermann, Karie Ellenen
kaust.authorHikmawan, Tyas I.en
kaust.authorZhang, Guishanen
kaust.authorStingl, Ulrichen
kaust.authorBajic, Vladimir B.en
kaust.authorKaur, Mandeepen

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