Characterization of solid UV cross-linked PEGDA for biological applications

Handle URI:
http://hdl.handle.net/10754/303702
Title:
Characterization of solid UV cross-linked PEGDA for biological applications
Authors:
Castro, David; Ingram, Patrick; Kodzius, Rimantas ( 0000-0001-9417-8894 ) ; Conchouso Gonzalez, David ( 0000-0002-9788-0977 ) ; Yoon, Euisik; Foulds, Ian G.
Abstract:
This paper reports on solid UV cross-linked Poly(ethylene)-glycol-diacrylate (PEGDA) as a material for microfluidic devices for biological applications. We have evaluated biocompatibility of PEGDA through two separate means: 1) by examining cell viability and attachment on cross-linked PEGDA surfaces for cell culture applications, and 2) by determining if cross-linked PEGDA inhibits the polymerase chain reaction (PCR) processes for on-chip PCR. Through these studies a correlation has been found between degree of curing and cell viability, attachment, as well as on PCR outcome.
KAUST Department:
Computational Bioscience Research Center (CBRC)
Citation:
Castro D, Ingram P, Kodzius R, Conchouso D, Yoon E, et al. (2013) Characterization of solid UV cross-linked PEGDA for biological applications. 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS). doi:10.1109/MEMSYS.2013.6474277.
Publisher:
Institute of Electrical and Electronics Engineers (IEEE)
Journal:
2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS)
Conference/Event name:
IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Issue Date:
20-Oct-2013
DOI:
10.1109/MEMSYS.2013.6474277
Type:
Conference Paper
ISBN:
978-146735655-8
Additional Links:
http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=6474277; http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6474277
Appears in Collections:
Conference Papers; Computational Bioscience Research Center (CBRC)

Full metadata record

DC FieldValue Language
dc.contributor.authorCastro, Daviden
dc.contributor.authorIngram, Patricken
dc.contributor.authorKodzius, Rimantasen
dc.contributor.authorConchouso Gonzalez, Daviden
dc.contributor.authorYoon, Euisiken
dc.contributor.authorFoulds, Ian G.en
dc.date.accessioned2013-10-20T11:13:30Z-
dc.date.available2013-10-20T11:13:30Z-
dc.date.issued2013-10-20en
dc.identifier.citationCastro D, Ingram P, Kodzius R, Conchouso D, Yoon E, et al. (2013) Characterization of solid UV cross-linked PEGDA for biological applications. 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS). doi:10.1109/MEMSYS.2013.6474277.en
dc.identifier.isbn978-146735655-8en
dc.identifier.doi10.1109/MEMSYS.2013.6474277en
dc.identifier.urihttp://hdl.handle.net/10754/303702en
dc.description.abstractThis paper reports on solid UV cross-linked Poly(ethylene)-glycol-diacrylate (PEGDA) as a material for microfluidic devices for biological applications. We have evaluated biocompatibility of PEGDA through two separate means: 1) by examining cell viability and attachment on cross-linked PEGDA surfaces for cell culture applications, and 2) by determining if cross-linked PEGDA inhibits the polymerase chain reaction (PCR) processes for on-chip PCR. Through these studies a correlation has been found between degree of curing and cell viability, attachment, as well as on PCR outcome.en
dc.language.isoenen
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)en
dc.relation.urlhttp://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=6474277en
dc.relation.urlhttp://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6474277en
dc.subjectbioMEMSen
dc.subjectmicrofluidicsen
dc.subjectmicrofabricationen
dc.subjectpolymersen
dc.subjectSurface treatmenten
dc.subjectBiocompatibilityen
dc.titleCharacterization of solid UV cross-linked PEGDA for biological applicationsen
dc.typeConference Paperen
dc.contributor.departmentComputational Bioscience Research Center (CBRC)en
dc.identifier.journal2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS)en
dc.conference.date20 January 2013 through 24 January 2013en
dc.conference.nameIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013en
dc.conference.locationTaipeien
dc.eprint.versionPublisher's Version/PDFen
kaust.authorKodzius, Rimantasen
kaust.authorFoulds, Ian G.en
kaust.authorCastro, Daviden
kaust.authorConchouso Gonzalez, Daviden
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