"Peak-tracking chip" (PTC) for bulk refractive index sensing and bioarray sensing

Handle URI:
http://hdl.handle.net/10754/303701
Title:
"Peak-tracking chip" (PTC) for bulk refractive index sensing and bioarray sensing
Authors:
Bougot-Robin, Kristelle; Austin, H. Robert; Benisty, Henri; Hsing, I-Ming; Kodzius, Rimantas ( 0000-0001-9417-8894 ) ; Li, Shunbo; Wen, Weijia; Zhang, Yinghua
Abstract:
Resonant techniques are of wide interest to detect variation of effective refractive index at a chip surface. Both Surface Plasmon Resonance (SPR) and dielectric resonant waveguide (RWGs) can be exploited. Through their design, RWGs allow more flexibility (size of the biomolecule to detect, detection angle…). Using specially designed RWG “Peak-tracking chip”, we propose to use spatial information from a simple monochromatic picture as a new label-free bioarray technique. We discuss robustness, sensitivity, multiplex detection, fluidic integration of the technique and illustrate it through bulk refractive index sensing as well as specific recognition of DNA fragment from gyrase A.
KAUST Department:
Computational Bioscience Research Center (CBRC)
Citation:
"Peak-tracking chip" (PTC) for bulk refractive index sensing and bioarray sensing
Publisher:
Royal Society of Chemistry
Journal:
MicroTAS
Issue Date:
20-Oct-2013
Type:
Article
Sponsors:
HKUST Special research fund initiative SRFIEG01; Hong-Kong government under the project SEG HKUST 10
Additional Links:
http://www.rsc.org/images/loc/2012/pdf/T.7.160.pdf
Appears in Collections:
Articles; Computational Bioscience Research Center (CBRC); Computational Bioscience Research Center (CBRC)

Full metadata record

DC FieldValue Language
dc.contributor.authorBougot-Robin, Kristelleen
dc.contributor.authorAustin, H. Roberten
dc.contributor.authorBenisty, Henrien
dc.contributor.authorHsing, I-Mingen
dc.contributor.authorKodzius, Rimantasen
dc.contributor.authorLi, Shunboen
dc.contributor.authorWen, Weijiaen
dc.contributor.authorZhang, Yinghuaen
dc.date.accessioned2013-10-20T11:10:00Z-
dc.date.available2013-10-20T11:10:00Z-
dc.date.issued2013-10-20en
dc.identifier.citation"Peak-tracking chip" (PTC) for bulk refractive index sensing and bioarray sensingen
dc.identifier.urihttp://hdl.handle.net/10754/303701en
dc.description.abstractResonant techniques are of wide interest to detect variation of effective refractive index at a chip surface. Both Surface Plasmon Resonance (SPR) and dielectric resonant waveguide (RWGs) can be exploited. Through their design, RWGs allow more flexibility (size of the biomolecule to detect, detection angle…). Using specially designed RWG “Peak-tracking chip”, we propose to use spatial information from a simple monochromatic picture as a new label-free bioarray technique. We discuss robustness, sensitivity, multiplex detection, fluidic integration of the technique and illustrate it through bulk refractive index sensing as well as specific recognition of DNA fragment from gyrase A.en
dc.description.sponsorshipHKUST Special research fund initiative SRFIEG01; Hong-Kong government under the project SEG HKUST 10en
dc.language.isoenen
dc.publisherRoyal Society of Chemistryen
dc.relation.urlhttp://www.rsc.org/images/loc/2012/pdf/T.7.160.pdfen
dc.rightsArchived with thanks to RSCen
dc.subjectBioarray imagingen
dc.subjectlabel-freeen
dc.subjectrefractive index sensingen
dc.subjectresonanceen
dc.subjectgratingen
dc.subject.meshComputer Simulationen
dc.subject.meshDNAen
dc.subject.meshGlycerolen
dc.subject.meshRefractometryen
dc.subject.meshSurface Plasmon Resonanceen
dc.subject.meshWateren
dc.subject.meshComputer Simulationen
dc.subject.meshDNAen
dc.subject.meshGlycerolen
dc.subject.meshRefractometryen
dc.subject.meshSurface Plasmon Resonanceen
dc.subject.meshWateren
dc.title"Peak-tracking chip" (PTC) for bulk refractive index sensing and bioarray sensingen
dc.typeArticleen
dc.contributor.departmentComputational Bioscience Research Center (CBRC)en
dc.identifier.journalMicroTASen
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionThe Hong Kong University of Science and Technology (HKUST)en
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)en
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